Monday 8 October 2012
side effects of anticancer drugs
Stiftung Warentest: anticancer drugs testStiftung Warentest published book "drugs in the test - Cancer"From tomorrow, the new book, "Drugs in the test - cancer" is the Stiftung Warentest available. On 272 pages, the Foundation informed independent and differentiated over the pros and cons of the various drugs used in cancer therapy. So the cancer patient is a self-assessment of drug treatment options are offered.In the book, typical issues of cancer patients, such as "What is the correct treatment?", "What are the side effects?" Or "how much suffering the quality of life?" Answered. Prior to the drug therapy to patients and their families can inform independently and objectively, so the release of the Stiftung Warentest.
Patients can inform authorities about side effects of drugs
patients to report side effects from todayOnline side effects of drugs report
On the Internet, there are several portals where patients can report adverse drug reactions. However, these websites operated commercially and usually serve only to share experiences of the patients. As of now, however, may report to the competent supervisory authorities concerned directly change and side effects of drugs. To this end, the Federal Institute for Drugs and Medical Devices (BfArM) and the Paul-Ehrlich-Institute (Pei) has called for vaccines in collaboration own portal into life.
Friday 6 July 2012
Side effects: Authority calls for smaller painkiller packs
Shelf with prescription packaging: painkiller sales should be restricted
Prepared for any situation: Many people buy painkillers at the pharmacy happy to supply. This should now be concluded. Because of possible side effects of aspirin, ibuprofen and Co. will in future only be sold over the counter in smaller packages.
If you always like to have a painkiller supply in the medicine cabinet is likely to be soon put off in small packages: Because of the risks to the free sales are restricted. Pharmacies, some of the most common pain relievers only sell in small packages without a prescription. Reason, the sometimes dangerous side effects of drugs that can occur when careless handling of the drugs.
Should be limited to packs of OTC pain relievers with the drug acetylsalicylic acid (ASA), diclofenac, ibuprofen and naproxen. The committee recommended a key at the Federal Institute for Drugs and Medical Devices (BfArM) in Bonn on Tuesday.
The final decision rests with the Federal Ministry of Health. "We will thoroughly examine the recommendation," said a ministry spokesman in Berlin.
Restricted painkiller sales due to side effects of pain killers
Restricted painkiller sales: "Four hours of action, four days of side effects"
Shopping before the holiday once again a large pack painkillers? In the future there will be something not good. Aspirin and other agents should only be in small doses without a prescription. The pharmacologist Kay Brune about the dangers of this Allerweltsmittel and their abuse.
No more storage packs of painkillers: The commonly used non-prescription pain relievers should in future only be available in small doses in the pharmacy: acetylsalicylic acid (aspirin), diclofenac, ibuprofen and naproxen are then only remain without a prescription in such quantities that are sufficient for four days. Paracetamol has been since 2009, only released in smaller packages for sale. It remains. These decisions, the expert committee of the Federal Institute for Drugs and Medical Devices (BfArM) taken now. The federal government has yet to approve the following, but in general the recommendations of the Committee. About the pros and cons of decisions Kay Brune, a pharmacologist at the University speaks of Erlangen-Nuremberg.
Pain medication would no longer be available in unlimited quantities.
Side Effect of Researcher: All known painkillers are likely soon only be available in smaller packs in order to protect the consumer. What makes them so dangerous?
Kay Brune: Available for sale does not mean harmless. In particular, the Allerweltsmittel aspirin and paracetamol can have serious side effects. Aspirin exerts its analgesic effect for about four hours, but side-effects show for four days. I'm talking about blood clotting disorders: The drug thins the blood. This effect does not end with the analgesic effect of the pill, but takes days long. Consumers who knows? Bleeding is the major risk of this drug.
Wednesday 7 December 2011
Side effects of painkillers cost Merck dearly
Side effects of painkillers
U.S. company Merck Vioxx costs nearly a billion
Authorities make the painkiller Vioxx for tens of thousands of heart attacks is responsible. The U.S. pharmaceutical giant Merck has taken it off the market years ago. The debate about the side effects continue to this day. Now, the manufacturer must pay nearly a billion dollars because he had sold the drug without approval.
The U.S. again Pharmarkonzern Merck paid almost a billion dollars to settle the dispute over the painkiller Vioxx. Merck has admitted to having sold Vioxx as a treatment for rheumatoid arthritis, before the U.S. Food and Drug Administration has granted to the appropriate approval.
Because of the side effects of the painkiller Vioxx, the U.S. manufacturer Merck has already paid nearly five billion dollars. Now added another 950 million.
A total of $ 950 million, the Group must now expend in order - roughly a third of which is attributable to a penalty, the remaining million of receivables from civil lawsuits. The pharmaceutical companies had already formed in the past year now agreed provisions in the amount of payment.
Merck & Co., not to be confused with the German drugmaker Merck KGaA, Vioxx had not only sold from 1999 as a painkiller, but also as a drug against rheumatoid arthritis. Only in 2004 the anti-inflammatory drug was withdrawn from the market after being linked with numerous heart attacks and strokes. In its advertising, however, have made Merck lied about the possible risks for the heart to the sales figures continue to push upward, said the Justice Department.
According to the U.S. Pharmacopoeia and Food Inspection FDA may for a period of five years 88000-139000 heart attacks are attributed to the ingestion of Vioxx. Up to 40 percent of which were fatal.
Already in 2007, Merck had reached an agreement out of court with the great majority of thousands of plaintiffs, which provided for the payment of 4.85 billion dollars. Then as now, the company said, it was not an admission of guilt connected.
U.S. company Merck Vioxx costs nearly a billion
Authorities make the painkiller Vioxx for tens of thousands of heart attacks is responsible. The U.S. pharmaceutical giant Merck has taken it off the market years ago. The debate about the side effects continue to this day. Now, the manufacturer must pay nearly a billion dollars because he had sold the drug without approval.
The U.S. again Pharmarkonzern Merck paid almost a billion dollars to settle the dispute over the painkiller Vioxx. Merck has admitted to having sold Vioxx as a treatment for rheumatoid arthritis, before the U.S. Food and Drug Administration has granted to the appropriate approval.
Because of the side effects of the painkiller Vioxx, the U.S. manufacturer Merck has already paid nearly five billion dollars. Now added another 950 million.
A total of $ 950 million, the Group must now expend in order - roughly a third of which is attributable to a penalty, the remaining million of receivables from civil lawsuits. The pharmaceutical companies had already formed in the past year now agreed provisions in the amount of payment.
Merck & Co., not to be confused with the German drugmaker Merck KGaA, Vioxx had not only sold from 1999 as a painkiller, but also as a drug against rheumatoid arthritis. Only in 2004 the anti-inflammatory drug was withdrawn from the market after being linked with numerous heart attacks and strokes. In its advertising, however, have made Merck lied about the possible risks for the heart to the sales figures continue to push upward, said the Justice Department.
According to the U.S. Pharmacopoeia and Food Inspection FDA may for a period of five years 88000-139000 heart attacks are attributed to the ingestion of Vioxx. Up to 40 percent of which were fatal.
Already in 2007, Merck had reached an agreement out of court with the great majority of thousands of plaintiffs, which provided for the payment of 4.85 billion dollars. Then as now, the company said, it was not an admission of guilt connected.
Diarrhea can be drug side effect
Diarrhea can be a side effect of various drugs. Quite often it occurs after taking antibiotics. He usually remains harmless. More than two days, he should pause, however. Then a doctor visit is appropriate.
Diarrhea can also be caused by medication.
Berlin - Diarrhea can be a side effect of various drugs. Quite often it occurs after taking antibiotics. He usually remains harmless. More than two days, he should pause, however. Then a doctor visit is appropriate.
"Diarrhea as side effects of antibiotics are usually harmless and disappear within a few days by themselves they hold more than two days, a doctor should be consulted," says Thorsten Gottwald of the Federal Chamber of Pharmacists, Berlin. Antibiotics kill bacteria and thus also some of the desirable intestinal bacteria. One possible result is diarrhea because nutrients are not completely degraded by the intestinal bacteria. Anyone who has diarrhea should drink a lot and replace the salt loss.
Various non-prescription medications can cause diarrhea as a side effect. This applies, for example, medications such as proton pump inhibitors that reduce the formation of stomach acid and taken for stomach pain and heartburn are. Known side effect is also contained in drugs for too much stomach acid, the magnesium. Anyone noticed this side effect can take up magnesium-free alternatives. Diarrhea is a side effect of cancer drugs, prescription heart medications or high doses of thyroid hormones.
"Diarrhea can also sign the overdose of a laxative to be," warns Gottwald. "Then you should reduce the dose of laxative until the stools soft but not liquid." Basically, laxatives without medical advice should not be used longer than two weeks. Exceptions are source materials from flaxseed or psyllium Indian: This laxative in high doses does not lead to diarrhea and can be taken long term.
Diarrhea can also be caused by medication.
Berlin - Diarrhea can be a side effect of various drugs. Quite often it occurs after taking antibiotics. He usually remains harmless. More than two days, he should pause, however. Then a doctor visit is appropriate.
"Diarrhea as side effects of antibiotics are usually harmless and disappear within a few days by themselves they hold more than two days, a doctor should be consulted," says Thorsten Gottwald of the Federal Chamber of Pharmacists, Berlin. Antibiotics kill bacteria and thus also some of the desirable intestinal bacteria. One possible result is diarrhea because nutrients are not completely degraded by the intestinal bacteria. Anyone who has diarrhea should drink a lot and replace the salt loss.
Various non-prescription medications can cause diarrhea as a side effect. This applies, for example, medications such as proton pump inhibitors that reduce the formation of stomach acid and taken for stomach pain and heartburn are. Known side effect is also contained in drugs for too much stomach acid, the magnesium. Anyone noticed this side effect can take up magnesium-free alternatives. Diarrhea is a side effect of cancer drugs, prescription heart medications or high doses of thyroid hormones.
"Diarrhea can also sign the overdose of a laxative to be," warns Gottwald. "Then you should reduce the dose of laxative until the stools soft but not liquid." Basically, laxatives without medical advice should not be used longer than two weeks. Exceptions are source materials from flaxseed or psyllium Indian: This laxative in high doses does not lead to diarrhea and can be taken long term.
Most accidents with blood thinners and insulin
If old people need to be hospitalized due to side effects, only a few drugs are involved. Trigger in two out of three cases, blood thinners or diabetes agents. Researchers warn that the problem could grow.
Polypharmacy exacerbates the risk of side effects.
ATLANTA (rb / ice). If old people need to be hospitalized due to side effects, only a few drugs are involved. Trigger in two out of three cases: Vitamin K antagonists, antiplatelet agents, insulins and oral antidiabetics.
Researchers at the U.S. Centers for Disease Control and Prevention have now compiled data on hospital treatments for severe adverse drug reactions of about 5000 patients aged 65 years in the USA (NEJM 2011; 365: 2002).
Half of those affected had been the 80th Age exceeded. In two thirds of cases of overdose had caused the incident.
Four drugs or drug classes were - individually or in combination - to 67 percent involved warfarin (33 percent), insulin (14 percent), oral antiplatelet drugs (13 percent) and oral hypoglycemic agents (11 percent).
Management for fewer hospital admissions
High-risk medications two spent only 1.2 percent of the events involved. These included the researchers about the antipsychotic thioridazine, the calcium channel blocker nifedipine and some long-acting benzodiazepines such as diazepam all have side effects.
Through improved management of antithrombotic and antidiabetic therapies themselves could avoid hospital admissions due to drug side effects, the researchers said.
They warn that the increasing polypharmacy in the elderly in the future will exacerbate the problem. So take 40 percent of the over-65s in the U.S. five to ten medications daily, 18 percent as much as ten or more drugs.
Polypharmacy exacerbates the risk of side effects.
ATLANTA (rb / ice). If old people need to be hospitalized due to side effects, only a few drugs are involved. Trigger in two out of three cases: Vitamin K antagonists, antiplatelet agents, insulins and oral antidiabetics.
Researchers at the U.S. Centers for Disease Control and Prevention have now compiled data on hospital treatments for severe adverse drug reactions of about 5000 patients aged 65 years in the USA (NEJM 2011; 365: 2002).
Half of those affected had been the 80th Age exceeded. In two thirds of cases of overdose had caused the incident.
Four drugs or drug classes were - individually or in combination - to 67 percent involved warfarin (33 percent), insulin (14 percent), oral antiplatelet drugs (13 percent) and oral hypoglycemic agents (11 percent).
Management for fewer hospital admissions
High-risk medications two spent only 1.2 percent of the events involved. These included the researchers about the antipsychotic thioridazine, the calcium channel blocker nifedipine and some long-acting benzodiazepines such as diazepam all have side effects.
Through improved management of antithrombotic and antidiabetic therapies themselves could avoid hospital admissions due to drug side effects, the researchers said.
They warn that the increasing polypharmacy in the elderly in the future will exacerbate the problem. So take 40 percent of the over-65s in the U.S. five to ten medications daily, 18 percent as much as ten or more drugs.
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